Mrs. Sanderson was admitted to the hospital with a severe methicillin-resistant Staphylococcus aureus (MRSA) infection. She is 84 years old, 5 ft 4 in. tall, and weighs 180 lb. She has normal renal function.

The physician has ordered Garamycin® 70 mg IM q8h. On hand: Garamycin® Injectable 40 mg/mL. According to the package insert, the usual dosage for patients with serious infections and normal renal function is 1 mg/kg q8h. Doses higher than this amount are considered unsafe. The ideal weight range for this patient is 122 to 157 lb.

If the ordered dose is safe, calculate the amount to administer.

The ideal weight range for Mrs. Sanderson is 122 to 157 lb. Her actual weight is 180 lb, which is higher than her ideal weight. Therefore, we need to adjust the ordered dose of 70 mg by multiplying it by her actual weight divided by her ideal weight.

This gives us an adjusted dose of 70 * 180 / 122 = 70 mg.

The package insert recommends a dose of 1 mg/kg q8h for patients with serious infections and normal renal function. Mrs. Sanderson's weight is 180 lb, which is equivalent to 81.6 kg. The recommended dose for her would be 1 * 81.6 = 81.6 mg. The ordered dose of 70 mg is lower than the recommended dose, so it is safe to give her the ordered dose. The adjusted dose of Garamycin for Mrs. Sanderson is 70 mg. This dose is safe because it is lower than the recommended dose for her weight.

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