High School

The linear range is the range of detected analyte mass using a chromatographic detector for which the factor remains constant, resulting in a calibration curve consisting of a straight line with a slope equal to the response factor.

Is this statement True or False?

a) True
b) False

Answer :

Final answer:

The statement about the linear range of a chromatographic detector being the range over which the factor remains constant and leads to a straight-line calibration curve is true.

Explanation:

The statement that the linear range is the range of detected analyte mass using a chromatographic detector for which the factor remains constant, resulting in a calibration curve consisting of a straight line with a slope equal to the response factor, is True. Within this range, a method's sensitivity remains constant, as the slope of the calibration curve gives the value of the response factor (kA). Furthermore, for analytes that demonstrate linear response over a significant concentration range, creating a robust calibration curve is possible. This linearity allows for quantification of unknown sample concentrations through extrapolation from the calibration curve.