High School

When is a kinetochore assembled onto the centromere?

A. During prophase
B. During anaphase
C. During telophase
D. During metaphase
E. During interphase

Answer :

Final answer:

The kinetochore is assembled onto the centromere during late prophase or "prometaphase" of mitosis. Microtubules from the mitotic spindle attach themselves to the centromeres of sister chromatids.

Explanation:

The kinetochore is assembled onto the centromere during late prophase or "prometaphase" to indicate the transition between prophase and metaphase of mitosis.

Near the end of prophase, microtubules from the mitotic spindle attach themselves to the centromeres of sister chromatids. The kinetochore, which is a protein structure on the centromere, serves as the point of attachment between the mitotic spindle and the sister chromatids.